Chemistry and discovery operations leader with >25 years of experience managing teams of scientists of widely varying professional levels and experience; experience with matrix management; extensive experience directing CRO research (US and overseas), including chemistry, ADMET/DMPK, and in vivo studies; experience managing medicinal, combinatorial, scale-up, and analytical chemistry groups, biologists, patent counsel, IT personnel, and compound management scientists. Experience with overall site management and building up groups.

Medicinal chemist with >30 years of experience in pharmaceutical research, ranging from early lead discovery to clinical drug candidate development. Experience in the appropriate use of med chem tools, including structure-based design, fragment-based optimization, parallel synthesis, and computational analysis. Co-inventor of lomitapide (Juxtapid^TM). Experience in a variety of drug target classes, including GPCRs, NHRs, kinases, proteases, epigenetic modulators, and protein-protein disruptors. Additional experience in design against targets for agricultural and personal care use.

Program leader with experience driving drug discovery programs through multiple stages in a variety of therapeutic areas, including metabolics, oncology, cardiovascular, antivirals, and bone. Extensive experience collaborating with and directing professionals from many different disciplines, including in vitro and cell biology, HTS, DMPK, in vivo pharmacology, informatics, intellectual property, program management, business development, and instrumentation.

Chemistry and discovery consultant with experience providing a broad palette of chemistry expertise to clients in the pharmaceutical, biotechnology, agricultural, legal, and academic environments. Entrepreneur coach for young scientists.