Design of effective therapeutic molecules

Early discovery chemistry triage to candidate developability

Lead optimization, hit-to-lead, and hit identification

Structure- and fragment-based design

Chemistry, biology, in vitro ADMET, DMPK, and tox studies

Multidisciplinary program management

Identification and assessment of worldwide resources

Appropriate use of FTE or FFS arrangements

Academic and small company tech transfer

Scientific due diligence; key information for investors

Analysis of small-molecule results and data packages

Approaches against various biological targets

Patentability searching, landscape analysis

Application assembly, liaison with patent counsel

Focus on novel composition-of-matter

SciFinder, STN, etc. experienced user (>30 years)

Detail-oriented with efficient data capture

Scope, time and resource management

Cohesive organization and communication channels

Focus on critical goals and effective paths

Key components of early stage company or project focus

Facilities and equipment procurement

Efficient operations management

Identification of critical team members